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Given that many combinatorial patterns only involve a few chromatin modifications [ 5], CoSBI is better suited for identifying subsets of re-occurring modifications given a compendium of histone modification maps.
Then given a compendium of N gene expression profiles, ChIP-PED searches among all biological contexts with at least three samples, for contexts that are associated with the regulatory pattern of interest (e.g. TF+TG+).
Therefore, each edge is interpretable as the posterior probability, given a large compendium of empirical data collected from human-derived samples, that two genes work together to carry out a specific biological process.
A compendium of Eurasian trade in goods, technology and ideas over millennia, it really does give a history of the world, up to the present war in Syria.
It's heartening to see that Sony hasn't forgotten about Sly Cooper and this superb-value compendium gives a new generation of gamers the chance to discover his thrilling escapades.
While most of his groundbreaking work on management was published before 1982, our panel gave a nod to the master, naming his The Essential Drucker (HarperBusiness; 2001) compendium as one of the most influential business books of the era.
To this end, we took advantage of a recently developed computational algorithm, named GENOMICA [19], which makes it possible to quantify and statistically evaluate the enrichment of one or more gene sets in all samples of a given microarray dataset compendium (Figure 3a).
It's appropriate that Something New is the song chosen to mark their 10-year anniversary, given that it sort of feels like a compendium of all their best bits.
One website I gave 4-stars to is the Vanguard News Network, a compendium of all things hate.
Specifically, detection of a compendium of metabolites in given organisms or communities can improve confidence in pathway-extension or hole-filing for sparsely annotated pathways [ 5- 7].
Given the microarray compendium scenario, we hypothesized that statistically significant correlation can still be detected using microarray, but strong correlation will be confined to a subset of samples/experimental conditions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com