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The GIF test for excess relatedness was performed for the 36 different cancer groups shown in Table 1.
We also present, for the first time for cancer, our expansion of the GIF test to include a test for excess distant relatedness (dGIF).
The empirical significance for the GIF test of overall familial clustering (both close and distant) is the same algorithm used to calculate the GIF in previously published reports on the familiality of cancer in Utah [ 3, 4].
The results for the overall GIF test show that for most of the cancer sites examined (28 of 36) there is a significant excess overall relatedness observed (without correction).
For the GIF test, since we have performed multiple tests (on 36 different cancer sites), we have adjusted our threshold for significance using the Bonferroni correction (noted to be conservative).
The GIF test estimates the average pair-wise relatedness between all possible pairs within a defined group of individuals (cases) and compares it to the expected average relatedness in the UPDB.
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Facebook tells me "GIFs can be a fun and compelling way to communicate, so we've started testing GIF support in posts and boosted posts for a small percentage of Facebook Pages.
The genealogical index of familiality (GIF) method that tests for a significant excess of relatedness of a set of cases compared with sets of matched population controls was modified.
The distribution of average relatedness from the 1,000 matched controls sets represents the expected relatedness in the UPDB population and can be compared with the case GIF for an empirical test of the hypothesis of no excess relatedness in the set of cases of interest.
It tested a GIF creator in Camera last month.
Instagram's initial tests of GIF sharing were first reported by The Next Web in November, but details were scarce and the product didn't have a "Giphy" logo in the search bar.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com