Primates genetically engineered to get neurological, human diseases could provide a unique way to test potential treatments.
When Lyme patients get neurological symptoms, the spinal fluid is in the majority of cases normal, because in the advanced state, the bacteria are intracellular and also in the brain, so they are no longer detectable in the spinal fluid.
It can take years before patients get neurological complaints or deficits.
"We understand the public's fear of getting a neurological condition, as some disorders can have such a major impact on someone's quality of life, independence and ability to communicate," Hogston said.
' (Arthur, aged 77 years) '... about 85% of men who've reached their 70th birthday are relatively impotent, and when you've got a neurological complaint as well [um].
Arthur, for example, who had spastic tetraparesis and a urethral catheter, explained why sex was not a problem that concerned him: '... about 85% of men who've reached their 70th birthday are relatively impotent, and when you've got a neurological complaint as well [um].
In this second stage of the disease, patients experience neurological symptoms, their sleeping routine gets completely disturbed and, without treatment, they eventually slip into a coma and die.
"They can't tell you, 'Well, this number means you'll get cancer,' or, 'This number means you'll have neurological problems or you'll have attention deficit.' What we do know is that these chemicals are very powerful agents.
"We don't understand all the risk factors for getting the severe neurological disease: why it is some people get the severe diseases and some don't".
Some can cause neurological disease.
