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This mapping sets the stage for (i) the design of specific inhibitors for the Vn fibrin interaction; (ii) for studying the role of this interaction in the anchoring of endothelial cells and platelets onto the fibrin clot; and (iii) for getting a deeper insight into the mechanism of the Vn fibrin interaction in fibrinolysis.
Subsequent analysis of the gene expression signatures will elucidate two critical issues for drug discovery: First, getting a deeper insight into a target's biology by identifying genes whose expression is transcriptionally altered after interfering with the target of interest, referred to as the TGF-β signature (on-target signature).
The results obtained allow getting a deeper insight into the role of the RNAi machinery in the regulation of endogenous processes in M. circinelloides.
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After getting a deep insight of the basic building blocks, people can use them to reconstruct new metabolic networks.
The present study will be a toehold for getting a deep insight in the brain function through a showcase of ventricular system, and for better understanding of the functional and developmental diversities of vertebrate cilia.
To get a deeper insight in this unexpected behavior, TD-DFT calculations were carried out.
This allows researchers to combine information from several years to get a deeper insight into the population's spatial requirements.
The aim is to get a deeper insight into the flame characteristics, to analyze stretching effects, and to investigate the type of the flame.
In the present work, we tried to get a deeper insight into the effect of the chemical composition of the SBA-15-type support on the development of NiMo and CoMo catalysts in deep hydrodesulfurization (HDS).
In order to get a deeper insight into the surface structure, chemical state, and stability of the electrocatalyst under reaction conditions, a combination of cyclic voltammetry, chronoamperometry and X-ray photoelectron spectroscopy (XPS) has been used.
DFT calculations were also carried out for a number of materials to validate the screening algorithm, applicability and reliability of the crystallochemical approaches as well as to get a deeper insight on the Na+ diffusion properties.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com