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"You get the sensitivity and thoughtfulness," he said.
With a linear fitting of the data, we get the sensitivity ΔS L of these long Cr/Pd thin film sensors to be 9.8 ± 0.5 μV/K.
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Subsequently the (Δ0,p, Σ0,p -data were set-averaged and smoothed in the same fashion as described above for the non-corrected intensities to get the sensitivity-corrected version of the hook-curve with the coordinates (Σ0,p -datahook).
To draw the sensitivity-specificity curves of the MetaProm prediction, we pooled predictions from the 10-fold cross-validation and ranked the MetaProm prediction scores (probabilities), and selected different cutoffs to get the Sensitivity-Specificity pairs at that cutoff.
"You're getting the sensitivity similar to PCR, but with proteins," Mirkin says.
A dynamic parametric sensitivity model (derived from the process model) is also used on line to get the parametric sensitivity that has to be optimized.
"We get the best sensitivity when the target is as close as possible to the nanotube," says Johnson.
The calibrated cantilever was ramped three times on the selected areas of 200 nm × 200 nm on the hard surface (silica) to get the updated sensitivity.
The cutoff value was set for each experiment independently, in order to get the best sensitivity and specificity and due to the fact that normalization standards do not yet exist.
As shown in Figure 4B, the read distributions of a simulated gene with 10 bins marked as methylated peaks and 90 bins as unmethylated, the corresponding detection results show that HEPeak can correctly detect 8 out of 10 true peaks, with 1 false positive, while ExomePeak results in 7 false positives to get the same sensitivity.
"I don't really get the security or sensitivity argument," he said.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com