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Somewhat related, it has been shown that finger representations get internalized especially in the first years of schooling.
Things like slamming a door or leaving garbage on the table after lunch in the boardroom: Those signals get internalized by everyone in the company.
Passive targeting implies that nanoparticles smaller than the fenestrations of endothelial cells extravagate at the leaky tumor vasculatures, penetrate, and get internalized into the tumor interstitium.
In fact, syndecan clusters elicited by the KKDC peptide appeared exceptionally large and failed to get internalized at the time points examined, while the heparanase-syndecan complex is rapidly and efficiently internalized (Fig. 2) [39].
Interestingly, while the heparanase-syndecan complex is subjected to rapid internalization and appears in endocytic vesicles short after the addition of heparanase, the KKDC peptide elicits syndecan clusters that remain on the cell surface for a relatively long period of time and fail to get internalized.
FPRs cluster into lipid rafts on the cell membrane upon agonist binding and then get internalized.
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The NDS (IONs) get internalize into the cell through cell membrane invagination, forming an early endosome that transformed into a late endosome within five minutes, then later a lysosome containing the particle and drug [18, 36, 37].
From a theoretical standpoint, the free dye contamination is much more problematic in terms of internalization by electroporation, as free dye gets internalized in preference to the protein.
And stigma, too, gets internalized.
As you get older, more and more of this gets internalized.
When any xenobiotic substance gets internalized into the cellular system, it may interact with genetic material such as DNA.
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