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We calculated sex and gestational age specific (SGA) z scores from birth weight and gestation data using British birth weight reference data from 1990 and an algorithm, following a standard procedure [ 17, 18].
A large number of these babies, almost 13,000, had fewer than 37 weeks' gestation or no gestation data.
All artiodactyl, carnivore, and primate species with both lactation and gestation data in PanTHERIA were included in the sample.
We found no evidence for main effects of PON1 genotype on either birth weight or length of gestation (data not shown).
In contrast, amniotic fluid glucose and β-hydroxybutyric, lactate, and uric acid concentrations did not differ across these weeks of gestation (data not presented).
We included all singleton elective CS delivery episodes in NHS trusts collecting gestation data, from 1st April 2000 to 28th February 2009.
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Preliminary experiments using Taf9b KO mice carrying the LacZ reporter gene suggest that Taf9b is highly expressed in the developing hypothalamus at mid-gestation (data now shown).
No significant differences were found between groups with regard to maternal pre-gestation weight, weight gain during pregnancy (data not shown), gestation at first antenatal attendance, gestational age at delivery and blood pressure at first antenatal attendance or maternal haemoglobin.
The NWH database of births consists of de-identified, prospectively collected maternity data for all births occurring at greater than or equal to 20 weeks of gestation, which includes demographic data, antenatal complications, and detailed delivery and newborn data.
Observed inhibition of GAS growth did not correlate with the gestation period (data not shown), and was instead patient specific and influenced by unknown factors.
Of the 154 women recruited in the first trimester, 45 had measurements taken at 12+0 12+6 weeks, 23+0 23+6 weeks, and 32+0 32+6 weeks of gestation; the data from these 45 women were also analyzed longitudinally.
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