Sentence examples for germ differentiation from inspiring English sources

In this study, we revealed that both in the spontaneous and RA-induced differentiation, the iPS cells could enter different germ differentiation stages.

These results suggest that Wnt signaling in ISCs regulates germ cell differentiation partly by preventing BMP signaling in the differentiation niche.

In monkeys, methods for inducing germ cell differentiation from ES cells have not been reported except spontaneous germ cell differentiation by EB formation [7].

We also believe that Piwi and Wnt signaling are relevant with each other in controlling ISC maintenance and promoting germ cell differentiation because they have similar mutant phenotypes in ISC maintenance and germ cell differentiation.

Importantly, integrated epigenetic mechanisms were explored during male germ cell differentiation, which provides deep insight into the epigenetic processes associated with male germ cell differentiation and possibly improves treatment options to male infertility in animals and humans.

It is possible that both differentiation-related transcription factors are involved in Pou5f1 regulation, suppressing its expression in the course of germ cell differentiation.

Finally, c587-mediated knockdown of GstD2 and Cat results in the ISC loss and the germ cell differentiation defect, indicating that ROS elevation in ISCs is sufficient to cause ISC loss and retard germ cell differentiation.

This pattern of germ cell differentiation and proliferation in the marmoset and human may result in an increased susceptibility to abnormal/incomplete germ cell differentiation and conditions that arise from this, such as CIS and TGCT.

Interestingly, germ cell differentiation proceeds normally in the germaria carrying extra ISCs, suggesting that ISCs provide a permissive environment for germ cell differentiation.

Simultaneous knockdown down of both fz and fz2 (fzKD+fz2KD) in ISCs recapitulate the germ cell differentiation defect caused by either armKD or dshKD, although either fzKD or fz2KD yields a much weaker germ cell differentiation defect.

Teixeira, F. K. et al. ATP synthase promotes germ cell differentiation independent of oxidative phosphorylation.