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The persistence of S. mansoni in Nder could raise concern as levels of infection intensity remain high (geometric mean intensity at baseline 653 epg changed to 705 epg at 12 months) after four rounds of chemotherapy.
In imMDDC from HIV-infected patients, the analysis of the intracellular expression of α-defensins1-3 showed a significant increase in the percentage of positive cells (24±4.8%; figure 1D) as well as in the geometric mean intensity compared to HCs (P<0.02; figure 1E).
* Geometric mean intensity, in mf/ml blood.
GM (Geometric mean) intensity is among the positive cases only.
This explains the variations in prevalence and geometric mean intensity across the different schools.
Geometric mean intensity of EPG for Trichuris was calculated for all participants.
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Geometric mean intensities for each bead were normalized to a standard recombinant protein curve for each cytokine.
Geometric mean intensities (GMIs) of microfilaraemia, CFA intensities and Bm14 OD-values were calculated as antilog [(Σlog x + 1)/n]-1, with x being the mf/ml, CFA units or OD-values, respectively, and n the number of individuals examined.
Geometric mean intensities (GMI) were calculated for non-normally distributed continuous variables such as S. haematobium egg counts and cytokine levels using the formula: antilog10 [(Σlog10 x + 1)/n)]-1, with n being the number of children examined.
The urine and serum samples from 158 children were analysed for levels of IL-6, TNF-α, IFN-γ and IL-10, and the geometric mean intensities (GMI) are shown in Figure 1.
Following 150 min of incubation with anti-Fas, most cells accumulated DDC and created a new peak of cells (red line) with a higher fluorescence intensity (the geometric mean fluorescence intensity value, GMFI, was 120.18) while the peak of late apoptotic cells remained unchanged.
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