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Cartesian grids with geometric adaptation are firstly generated automatically with boundary cells processed by cell-cutting and cell-merging algorithms.
This geometric adaptation tells apart native from misfolded structures, and hence introduces a physical constraint guiding the design of loose peptide-based materials that must remain water-tight to maintain structural integrity.
There are very few computational models available to study LV geometric adaptation with aging.
In this study we showed that six months of exercise were associated with mid-femur cortical bone geometric adaptation.
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I am being flippant, but the truth is that GINA (which stands for "Geometric Infinite Adaptation") is a stunning piece of work that could change the way cars are designed for ever – but won't.
Another popular model for understanding adaptive evolution is Fisher's geometric model of adaptation [ 45, 138- 144].
Pleiotropy also plays a central role in Fisher's geometric model of adaptation, which explains limitations on the rate of adaptation due to pleiotropic constraints on effect sizes of beneficial mutations (Fisher 1930).
True to Fisher's original presentation, the geometric model of adaptation is rarely visualised as an adaptive landscape despite the underlying conceptual similarities.
The most integrated vision of complexity comes from Fisher's geometric model of adaptation [ 13].
Using Fisher geometric model of adaptation, several theoretical studies have also analyzed the consequences of phenotypic complexity on evolution.
Fisher's geometric models of adaptation predicts that small phenotypic changes should have a higher probability of being advantageous (Fisher 1939) (but see [ Kimura 1983; Orr 2002]).
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