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The study area is a geographically continuous area comprising 50 villages in the Muzaffarpur District of Bihar State, India, a district where VL is highly endemic.
However, haplotypic matches occur only between geographically continuous regions, in the west linking the Maghreb up to Atlantic Europe and down to the Canaries and West Africa, and in the east the Levant with the Arabian Peninsula.
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Ralph and Coop (2010) studied parallel adaptation with simulations in a continuous, geographically spread population.
Local TV stations will be able to play the game, too, offering continuous news and geographically targeted advertising.
Indeed, the significant correlation coefficients found between LC T*Pfrequencies, latitude and longitude are better explained by a pronounced genetic differentiation between a few geographically distant populations than by continuous patterns of frequency variation.
When once-continuous populations are isolated geographically from each other, a situation termed allopatry (living in different places), they begin to accumulate mutations unique to their geographic group, and the process of genetic divergence begins.
These negative evolutionary relationships between N fixation and geographically weighted SA are significant for the continuous treatment of N fixation but marginally (SAW-max) or not (SAW-mean) significant for the discrete (more conservative) treatment (Table 1).
The process involves the separation of a once-continuous range into two or more geographically isolated, or allopatric parts, which over time accrue genetic changes that result in new daughter species.
Parapatric species are defined as species that have at least one other closely-related species which inhabits a continuous range, the two species excluding each other geographically [15], [33].
Since both samples were geographically clustered we used linear mixed effects models for the continuous outcomes and logistic regression mixed effects models for the binary outcomes, with a random effect fitted for clustering in all models.
The 2 integration centres offer identical services, each to half of the 18 study centres (divided geographically into a northern and a southern region), and will ensure continuous mutual back-ups of the full datasets collected from all 18 centres.
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