Sentence examples for genuine target of from inspiring English sources

We found that the DYNC1H1 mRNA is likely to be a genuine target of tRNase ZL (Figure 6), and the two RNA fragments co-immunoprecipitated with tRNase ZL suggest that the β-actin-like protein mRNA and the DOCK9 pre-mRNA may also be genuine targets (Table S1).

Upd is a genuine target of miR-279 that regulates circadian rhythms (Luo and Sehgal 2012).

Thus, our data provide the experimental evidence that ARL2 is a genuine target of miR-195 in hESC-NPCs.

Our study is the first to have identified FOXO1 as a genuine target of miR-196a, suggesting a crucial functional role of FOXO1 in cervical tumorigenesis.

A growing body of literature has demonstrated the importance of these stem cells to propose an explanatory model for gliomagenesis that could possibly open the way to major therapeutic progress, as these cells constitute the genuine target of treatments.

In our view, the key criterion for demonstrating that a particular mRNA is a genuine target of TTP or one of its family members is a demonstration that the stability of the transcript is increased in cells deficient in the protein.

Such kind of nucleotide modification may alter genuine targets of let-7a.

They also support the idea that genuine targets of microRNAs share common regulatory characteristics with the microRNAs in addition to the binding site on the target 3'UTR.

There are only 27 target genes shared by both unedited and edited forms, suggesting that editing does change the genuine targets of let-7a.

We also demonstrated that the PPM1F mRNA is one of the genuine targets of tRNase ZL guided by 5'-half-tRNAGlu.

These results suggest that the PPM1F and DYNC1H1 mRNAs are genuine targets of tRNase ZL guided by 5'-half-tRNAGlu and the 28S rRNA fragment, respectively.