Sentence examples for genuine locus from inspiring English sources

Possible linkage disequilibrium between HLA loci has been a thorny issue when researchers tried to identify the genuine locus responsible for the association signal [11], [15], [17].

However, for g = 8, the peak around the genuine locus is made much more evident when using the 4-track model than when using either P link or M erlin, maintaining this relative performance for g = 10.

In general, GWAS does not distinguish a genuine causal locus from those statistically significant loci within a strong LD region.

The stronger association that we observed in this clinically distinct subgroup (females with early onset), within a region where linkage disequilibrium was not significantly extended, suggested that the genuine RA locus should locate either within or close to the IL-3 gene.

While the firing time of the genuine ARS609 locus was around 70 min after the release from G1 arrest (Figs 1H, 2D), the recruitment of Cdc45 was shifted 40 min forward in the HXK1-ARS607 locus and peaked at 30 min after the release from G1 (Fig 4J).

Genuine miRNA loci produce so-called mature (miR) and star (miR*) sequences (originated from the preferred and non-preferred strands of miRNA duplex, respectively) that can be derived from both arms of the miRNA precursor.

This demonstrates that adjusting for GPCs has two effects the first being to reduce spurious signals and the second being to increase the correlation between real and detected signals at genuine associated loci, although the optimal number of GPC correction may be different for these two goals.

Our meta-analyses which include nine independent studies comprising 9,072 individuals provide good evidence that GAB2 (rs10793294 OR = 0.78, p = 0.007) is a genuine candidate LOAD locus.

In addition, de novo assembly of the remaining reads did not generate contigs that would point to additional genuine siRNA-producing loci (data not shown).

Variants rs2043211 (CArs1143623143623 (IL1B) and rs2569190 (CD14), which were associated with gout, are functional variations in genes directly involved in the NLRP3 signaling pathway, and as such are likely to represent genuine disease-susceptibility loci.

Since "there is no universal [of being] whatsoever that subsumes the I and the thou" (NKZ VI, 381), the locus of genuine interpersonal encounter must be thought of in terms of the place of absolute nothingness (see Davis 2014).