Sentence examples for genotyping stage from inspiring English sources

Using two DNA pooling stages to enrich true positives, each of around 1,000 children selected from the extremes of the distribution, and a third individual genotyping stage of over 3,000 children to test for quantitative associations across the normal range, we aimed to home in on genes of small effect.

aNumber of single-nucleotide polymorphisms (SNPs) in the initial genotyping stage.

For our stage 2 analysis, we sought follow-up samples with pre-existing GWAS in silico data (stage 2a) as well as de novo genotyping (stage 2b).

The sample for the individual genotyping stage comprised 2356 individuals (one member of each twin pair) drawn from a normal distribution of mathematics scores.

For the CNV genotyping stage, we assigned individuals to each CNV cluster according to the log2 ratio between test sample and reference sample.

Ultimately, individual genotyping would have provided greater information in Stage 1. Financial considerations meant that the number of SNPs that could be followed up in the individual genotyping stage was constrained to approximately 20 SNPs per study.

We applied similar filters to the newly genotyped Stage 2 samples.

Analyses of the newly genotyped Stage 2 data (i.e., all Stage 2 studies except ANECS/SEARCH or SECGS) were adjusted for study and the first four principal components.

Thus, 85 SNPs whose position was representative of the overall marker distribution were eligible for genotyping for Stage I.

Among heavy metals, As, Cd, Hg, Pb and Ni are the most important to consider in terms of food contamination [16, 20, 21], which depend on many complex factors like level and duration of contaminant exposure, agronomic management, plant genotype, stage of plant development at harvest time [16].

Without multivariate analysis, patients with FokI C/C genotype, stage I disease, or without residual tumour after surgery did show a significantly reduced crude hazard ratio.