Exact(1)
These molecules also show the genotypic consequences of Cdk4 enzyme inhibition at the cellular level, that is, growth inhibition of cancer cells in vitro, arrest of asynchronous cells at G0/G1 and prevention of pRb phosphorylation at Cdk4-specific serine residues.
Similar(59)
These cases show that plants can thrive across a broad temperature range, but that temperatures beyond genotypic thresholds evoke consequences such as cell death - as demonstrated by Zhang et al. - poor greening, and male sterility.
Some of this variation may not have significant phenotypic consequences since genotypic frequencies inferred from PCR products amplified from a large sample of outbred flies matched Hardy-Weinberg expectations.
Additionally, the complete sequencing of the Przewalski's horse genome (or exome) and its detailed comparison with the domestic horse genome is expected to facilitate the discovery of genotypic differences of phenotypic consequences distinguishing these two closely related species.
Furthermore, better visualization approaches are needed for studying phenotypic consequences of combinatorial genotypic effects in a temporal context.
Genetic changes occur as a consequence, because the genotypic fitnesses may shift so that different sets of alleles are favoured.
Disease etiology may be regarded as a consequence of both genotypic and biochemical phenomena, which impact individual patients in different ways.
To some degree, this is likely to be a consequence of the genotypic heterogeneity of tumours.
It is a clear consequence of the genotypic approach of replication that, unless certain conditions are met, the replicator is not necessarily a unit of evolution.
As a consequence, the random effect predictions are genotypic and not breeding values.
In principle, the observed gene expression differences between PC and RI could arise due to genotypic differences or as plastic downstream consequences of behavioral differences (awake vs. sleeping).
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