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Detailed week-by-week analysis for individual patients and genotype groups is shown in Supplementary Fig. 3a,b.
No sociodemographic differences between these two genotype groups were present for gender, age and educational level (data not shown).
The full week-by-week analysis for intrinsic membrane currents for individual patients and genotype groups is shown in Supplementary Fig. 6a,b.
With respect to performance, the two genotype groups did not differ significantly except on immediate memory, with the epsilon4 group exhibiting increased errors.
For VT, genotype groups were analysed separately.
Staphylococcus aureus obtained during the study comprised isolates from 12 different genotype groups as defined in this study.
PCAs were performed independently for PET1 and PET2 after z-score standardisation of VT values within genotype groups.
Renal function was assessed among apolipoprotein E genotype groups by comparisons of preoperative (CrPre), peak in-hospital postoperative (CrMax) and perioperative change (DCr) in serum creatinine values.
Log-rank test and Cox proportional hazard models were used to compare SPM-free survival and SPM risk between the different genotype groups.
All genotype groups obeyed Hardy-Weinberg equilibrium.
All genotype groups were in Hardy-Weinberg equilibrium (Table 2).
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