Sentence examples for genotype dosage from inspiring English sources

Predicted animal-specific imputation accuracies were derived using selection index theory [ 26], assuming genotype dosage is a trait with a heritability of 1 (assuming no genotyping errors), which provides the accuracy of a linear prediction of gene content.

Variance of expression of ENSG00000232629 ( HLA-DQB2 ) is dependent on genotype dosage of rs114183935.

Variance of expression of ENSG00000196735 ( HLA-DQA1 ) is dependent on genotype dosage of rs9276807.

Also for the SNP-specific imputation accuracy, genotype dosage probabilities were used, rather than the most likely genotypes.

However, these missing SNP genotypes did receive genotype dosage probabilities and these were included when calculating the imputation accuracy.

An interaction term between each of these variables and the genotype dosage was added to the above models.

Imputed markers in the NHS-T2D study were analyzed using genotype dosages (expected allele counts).

SNP-specific imputation accuracy was defined as the correlation of true genotypes with imputed genotype dosages per SNP across individuals.

We used SNPTEST (v2.5) (57) to test associations of 2610 imputed SNPs (minor allele frequency >0.01) with the same SUA trait in the frequentist additive model using genotype dosages.

For comparisons with previous studies, we also computed the commonly used uncorrected accuracy of imputation per individual (runcorrected) based on the correlation of true genotypes with imputed genotype dosages.

Associations between each SNP and endometrial cancer were estimated using unconditional logistic regression with a per-allele (1df) model, based on the expected genotype dosages for the imputed SNPs.