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However, powerful functional genomics technologies for finding and mutating mosquito genes as well as regulating transgene expression, such as enhancer- and gene-trap technologies, have been lacking.
This is a pity since the application in model fish of many new genomics technologies, for instance in epigenetic analysis [ 94 98], will be more difficult to translate to comparative epigenetic studies in other fish species and mammals.
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Dr. Singer then described an ethical framework and approach to priority-setting for genomics technologies in health care institutions.
The enormous potential for genomics technologies to improve patient care has been recognized, but it will not be reached unless powerful but secure data-sharing technologies are developed.
The advent of whole genomics technologies provides necessary tools for identifying the key gene networks that respond to drought stress [ 77].
The data from high throughput genomics technologies provide unique opportunities for studies of complex biological systems, but also pose many new challenges.
The enormous potential for genomics technologies to improve patient care has been recognized in fields as diverse as rare diseases, cancer, immunology, infectious diseases, prediction of medication side effects, and therapy stratification for patients with common diseases.
Together, these fundamental and applied scientific purposes have made it possible that the most advanced genomics technologies have been used for studies of many bony fish species, ranging from the model fish species zebrafish and medaka to 'living fossils' such as the coelacanths and the fresh water eels [ 5 11].
The technology will become an integral part of Church's other brainchild, the Personal Genome Project, an effort to enable personalized medicine by providing a test bed for new genomics technologies and analytic tools.
The ENCODE project has also released minimum standards for many genomics technologies [ 16].
Next, Dearfield et al. describe the current strategy of the U.S. EPA in attempting to create a framework for using genomics technologies.
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