Sentence examples for genomic utility from inspiring English sources

This has potential to severely compromise clinical genomic utility, as indels are a major class of pathogenic variant, and are routinely and robustly detected by pre-NGS mutation detection methods, such as Sanger sequencing.

The Genomic Utility for Automated Comparison (GUAC) Python script (Additional file 5) was developed to inform comparative analyses of gene content across multiple genomes, in particular genes involved in sulfur-oxidation and extracellular transport (Table 2).

Numerous professional organizations have conducted evidence reviews, and at the federal level, the need to produce evidence-based recommendations on validity and utility of genomic applications in medicine was recognized by the creation of the Evaluation of Genomic Applications in Practice and Prevention (EGAPP) working group (Teutsch et al. 2009).

These findings emphasize the utility of genomic approaches for determining invasion mechanisms, through analysis of gene expression, gene interactions, and genomic rearrangements that are associated with invasion events.

These applications demonstrate the utility of genomic tools, and illustrate the applicability of emerging next-generation sequencing technologies.

We have tested the utility of genomic flank-sequencing on three plasposon mutants of the soil bacterium Collimonas fungivorans with abolished ability to degrade chitin.

Randomized controlled trials offer a rigorous framework within which to evaluate the clinical utility of genomic interventions (i.e., the intervention's potential to improve patient outcomes).

Through quantitative and qualitative measures, including baseline and post result disclosure surveys, post result disclosure interviews, 1 2 year follow-up interviews, and team journaling, we are obtaining data about the clinical and personal utility of genomic carrier screening in this population.

Our study demonstrates the potential clinical diagnostic utility of genomic imbalance profiling in VSD patients.

Finally, there is little scientific evidence regarding the clinical utility of genomic interventions [ 8].

The integrated map described herein enhances the utility of genomic tools over previous watermelon genetic maps.