Sentence examples for genomic techniques such from inspiring English sources

This is so because genomic techniques such as the agnostic search of the genomes of individuals with disease compared with those without disease (called a genome-wide association study, GWAS) requires large numbers of study participants, usually in the thousands, to have adequate statistical power to find an association if one exists.

The use of modern genetic and genomic techniques, such as quantitative trait locus (QTL) mapping, genomic selection, genome-wide association studies (GWAS), and genetic engineering, can accelerate the pace of disease resistance locus identification and trait improvement.

The availability of complete genome sequences, the advances in microarray technologies, and the development of novel functional genomic techniques such as 'chromatin profiling' facilitate dissection of the interplay among transcriptional networks and reveals chromosome organization in vivo.

For example, genomic techniques such as DNA microarray analysis (examining 4968 significant genes) [7] and RT-PCR analysis of formalin-fixed, paraffin-embedded tissues (examining 21 prospectively selected genes) [8] have been used for chemotherapy treatment planning in breast cancer.

Genomic techniques, such as DNA microarray analysis, and proteomic methods, such as two-dimensional (2-D) electrophoresis and mass spectrometry, are now commonly used to elucidate the expression profiles of genes and proteins in cells, tissues and bodily fluids [14], [15].

Currently, only genomic techniques such as PCR are available for laboratory diagnosis of virulence markers.

These features would escape from detection by expression profiling (or any other genomic technique such as comparative genome hybridization on arrays) unless one analyzes each potentially unique cell population within a tumor, an impossible enterprise.

Bioinformatic analyses such as this one represent useful and informative tools for reducing experimental search space, particularly when combined with other post-genomic techniques such as microarray analyses.

Current genomic sequencing techniques, such as deep DNA sequencing, provide the opportunity to systematically analyze the complete genome on a large scale, resolving the extent of intra-tumor heterogeneity at unprecedented detail at the single-nucleotide level.

In addition, athletes will also seek advantage over their opponents using genomic medicine techniques such as exon-skipping to restore dystrophin expression in Duchenne muscular dystrophy that increases "natural" muscle size and strength possibly improving performance [ 38].

Unlike traditional genomic annotation techniques, such as in silico (ab initio or comparative) or cDNA-seq-based methods, proteogenomics allows validating protein-coding genes directly at the protein level, which is more favorable (Renuse et al., 2011).