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Nevertheless, the genomic structure, the intronic primer sequences, and polymorphisms of the hMAD2 gene presented here will facilitate future studies to determine the full spectrum and frequency of the genetic events that can affect expression of the hMAD2 gene in human tumors.
We concluded that this molecule is a bone fide fish ortholog for mammalian Fas by several lines of evidence: its domain structure, similarity of its genomic structure, the conservation of synteny of the Fas gene-containing genomic region between humans and Medaka, a molecular phylogenetical evidence and the functionality of the Medaka Fas death domain for the transmission of apoptotic signals.
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We considered prediction of genomic structures the way they are annotated in GenBank.
The present study identifies the genomic structure and the gene content of the TRA/TRD locus in the Ovis aries whole genome assembly.
To determine the genomic structure of the human TXNRD1 gene, the human genome data from the NCBI database was searched using the TXNRD1 cDNA [ 8] sequence.
The coding region of the rat Sin1 cDNA was then used to search the rat genome database at the NCBI website for the genomic structure of the gene.
The genomic structure of the Mst77Y region and the possible existence of additional copies remained unknown.
We studied the genomic structure of the M6P/IGF2R gene and designed the intron primers to detect mutations in the M6P/IGF2R gene of genomic DNA samples.
The availability of bioinformatic tools enabling comparative analysis and the finalisation of the human genome prompted us to re-examine the genomic structure of the ghrelin locus.
Using the genome sequence of strain EIB202 as the reference, we compared the genomic structure among the eight strains by contig mapping.
They conclude that the genomic structure of the bacteria has evolved to meet the requirement for adaptation to the rhizosphere and interaction with host plants.
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