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Their genomic structure is usually modular, with genes of related functions clustered in the genome with their sites of action.
Genomic structure is not equal across the species distribution.
Although cDNA sequences of AcFREP1 and AcFREP2 are 81% identical, their genomic structure is entirely different: AcFREP1 is intronless and AcFREP2 is encoded in four exons.
Their genomic structure is believed to be highly correlated to the transcription mechanisms underlying their collinear expression [25].
However, the explanation for the evolutionary conservation about this genomic structure is still insufficient.
Such genomic structure is similar to several other newly designated integrases/transposases.
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Genomic structure was determined by searching the zebrafish genome (http://www.ensembl.org/Danio_rerio/index.html).html
Genomic structure was determined by searching the zebrafish genome (http://http://www.ensembl.org/Multi/blastview?species=Danio_rerio) followed by PCR analysis.
The genomic structure was subsequently confirmed by long-range PCR amplification and restriction analysis in all sequenced strains (Supplementary Table S2).
Later, the exact ovine genomic structure was determined using the experimentally derived ovine mRNA sequences.
Similar observations on tree topology, protein domains, and genomic structure were made for Nme6 (Figure 3).
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