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Sequence similarity is calculated by BLAST, whereas genomic function and genomic structure are estimated by COG and operon annotation, respectively.
Both the similarities and differences in genomic structure are critical to the interpretation of rodent models for human disease.
Ty3/Gypsy retroelements, which are similar to vertebrate retroviruses in both sequence and genomic structure, are broadly distributed among eukaryotes [ 25].
To resolve the above puzzles, the correlations for gene expression pattern and primary genomic structure are re-examined for the flowering plants Arabidopsis and rice.
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Genomic structure was determined by searching the zebrafish genome (http://www.ensembl.org/Danio_rerio/index.html).html
Genomic structure was determined by searching the zebrafish genome (http://http://www.ensembl.org/Multi/blastview?species=Danio_rerio) followed by PCR analysis.
Their genomic structure is usually modular, with genes of related functions clustered in the genome with their sites of action.
Although cDNA sequences of AcFREP1 and AcFREP2 are 81% identical, their genomic structure is entirely different: AcFREP1 is intronless and AcFREP2 is encoded in four exons.
Later, the exact ovine genomic structure was determined using the experimentally derived ovine mRNA sequences.
Similar observations on tree topology, protein domains, and genomic structure were made for Nme6 (Figure 3).
Their genomic structure is believed to be highly correlated to the transcription mechanisms underlying their collinear expression [25].
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