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However, even with more advanced interspecies comparisons, on a genomic scale the true positive TF-TG interactions are spread out across many other high-scoring interactions.
We investigated, for the first time on a wide genomic scale, the latitude-driven adaptation phenomena.
Even at this small genomic scale, the data are very incomplete owing to idiosyncratic coverage of SNP pairs.
At a genomic scale, the patterns that have shaped molecular evolution are believed to be largely heterogeneous.
Here we test this prediction by exploring on a genomic scale the mRNAs associated with FOG-1 and FOG-3.
We investigated, at the genomic scale, the common selective constraint (probably associated with conservation of function) in homologous, but highly divergent, noncoding sequences.
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At large or genomic scales, the patterns that have shaped molecular evolution are largely heterogeneous.
The strongest known predictor of amino acid composition at the genomic scale is the GC content of the coding DNA sequences [ 2, 23].
Last but not least, the genomic scale of the available data necessitates the development of efficient tools for tackling the task of strain tree inference.
Although we use and report the uncorrected Platt scores here simply as a means to show enrichment for targets, we outline the calculations necessary to correct these scores to the genomic scale in the Methods section.
In addition, all chromosomes of Tetraodon nigroviridis were assigned to syntenic groups of duplicated genes, demonstrating the genomic scale of the duplication.
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