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In addition, all chromosomes of Tetraodon nigroviridis were assigned to syntenic groups of duplicated genes, demonstrating the genomic scale of the duplication.
Last but not least, the genomic scale of the available data necessitates the development of efficient tools for tackling the task of strain tree inference.
Another important result of our study is the confirmation at wide genomic scale of the occurrence of indel slippage (Zhu et al. 2000).
Geographic population differentiation in Atlantic cod appears to be distinguished by a few discrete islands of genomic divergence, although finer-scale sequence analysis and selection experiments are needed to further resolve the genomic scale of divergence.
However, because of the large state space of genealogies that has to be explored by the importance sampling algorithms for a multilocus ARG, this approach is intractable on a genomic scale of hundreds of kilobases.
Our results show that, at any given time point, more than 1500 genes, or about 3.8% of those assayed are differentially expressed between wild and domesticated G. hirsutum, showing the genomic scale of gene expression change accompanying an altered developmental allometry within a single cell (increased fibre length in domesticated TM-1).
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However, the use of data at the genomic scale to reconstruct the phylogeny of organisms also attracted a lot of interest recently (see [ 4] for review).
The phenomic method of time series analysis of cell array images provides growth curves on a genomic scale for measuring strength of gene interaction [ 13].
For example, Filliol et al. [ 13] examined phylogeny inference on a genomic scale for the purpose of categorizing genetic variations from geographically diverse isolates of Mycobacterium tuberculosis.
These frequencies were plotted logarithmically on a genomic scale to distinguish regions of high TE content from low copy regions.
Given the potential of BiP to regulate the UPR and the capacity of the BiP overexpressing plants to maintain leaf turgor under water deficit conditions [ 13, 14], we reasoned that a genomic scale profile of the shared responses of ER and osmotic stresses would provide insights into the mechanism of BiP-mediated increases in osmotic balance under stress conditions.
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