Sentence examples for genomic scale and from inspiring English sources

Previous comparative analysis of these three genomes was performed at a genomic scale and strain-specific differences were demonstrated, but high rates of conservation were detected in regions of rearrangements, which were probably involved in pathogenesis.

The authors concluded that the simple methods largely outperform the complex ones at the genomic scale, and proposed a new model for TIS recognition at the genome level that combines the strengths of these simple models.

Functional genomics approaches, such as whole-genome sequencing, are powerful tools for the analysis of specific traits on a genomic scale and provide a method of studying cellular physiology from micro-perspective.

The reduced computational cost at the coarse-grained level of abstraction will potentially enable both folding studies on a genomic scale and systematic application in protein design.

Non-domain regions of proteins clearly play a major role in adaptive protein evolution on a genomic scale and merit future investigations of their functional properties.

The study of expression quantitative trait loci (eQTL) is a powerful way of detecting transcriptional regulators at a genomic scale and for elucidating how natural genetic variation impacts gene expression.

(It must be observed, however, that this theory operates on much larger genomic scales and refers to isochores that cover from hundreds of thousands to millions of bases).

This library provides an unprecedented view of likely sequences of mutational events in local regions of the genome that may give us new insight into mechanisms of mutation and selective pressures on genomic scales and in individual genes of interest.

Over the last five decades, the molecular clock has been central to debates in evolutionary biology (i.e., selectionism vs. neutralism), and provided a basis for estimating the divergence time of populations and species, detecting natural selection at genomic scales and understanding the origin of sequence variations (Rannala and Yang 2003; Kumar 2005; Yang and Rannala 2012; Du et al. 2013).

Our results identify NF-κB as the key regulator of the universal TLR response and the ISRE element as the key control site of the TLR3/4 specific component, and reveal, on a genomic scale, known and novel target genes regulated by these elements.

The development of genomic scale information and its use to conduct global transcriptomic, proteomic, and metabolomic analyses is a major goal of the legume research community [ 16, 22].