Sentence examples for genomic replacement from inspiring English sources

Our hypotheses could be investigated in vivo by using a strain of Acinetobacter baylyi sp. ADP1 in which the efp gene has been replaced by a tagged version by using genomic replacement as described previously in Metzgar et al [ 36].

We have devised a strategy (called recombinase-mediated genomic replacement, RMGR) to allow the replacement of large segments (>100 kb) of the mouse genome with the equivalent human syntenic region.

A 2.6 kb DNA fragment containing the genomic replacement of HAC1 with KanMX and flanking regions was amplified by PCR using primers KT007/KT008 (Additional file 8).

For a population in steady state, we have, see Additional file 1: Appendix S1, (5) φ = θ 1 + θ or θ = φ 1 - φ. Hence, genomic fluidity has a one-to-one relationship with θ, the relative rate of gene uptake to genomic replacement.

To better document to what extent genome replacement takes place in this old lineage, nuclear gene genealogy between sexual species and their corresponding genomic contributions in various unisexual populations across the range could be the key to understand this process.

The present discovery of commonality of genome replacement in unisexual Ambystoma suggest that it has probably been an important factor in the evolution of this complex, and the unisexual Ambystoma likely have much more dynamic genomic histories than previously believed.

Both genomic substitution involve short segmental replacements of a few genes (7 and 8), and the second an almost reciprocal recombination between homeologous chromosomes that cannot be observed by aCGH analysis.

Genomic crtI replacements were used to swap the native three-step Rba.

The second type are the "replacement genomic islands", in which completely different gene clusters with similar assigned functions are found at the same genomic location.

Plasmid pFvL921 was made by amplification of the RPD3 ORF from genomic DNA and replacement of Dot1 in pFvL230 by gap repair.

The histogram shows the distribution of the average divergence for 1000 null data sets generated by resampling the genomic background without replacement.