Sentence examples for genomic profiling with from inspiring English sources

Further, a customized array design can provide comprehensive genomic profiling with additional accuracy in both identifying and defining the extent of small aberrations at target loci.

We conducted a comprehensive study to further investigate the influence of the dietary carbohydrates on S. mutans-transcriptome at distinct stages of biofilm development using whole genomic profiling with a new computational tool (MDV) for data mining.

Using genomic profiling with OncoMap coupled with an analytical mutation-calling algorithm and orthogonal validation step, numerous mutations have been identified in genomic DNA from both frozen and FFPE tumor tissue with a high degree of specificity and sensitivity[ 21].

We describe a novel TNKS2 PDGFRA fusion in a myeloid neoplasm with eosinophilia, detected via comprehensive genomic profiling with a next-generation sequencing-based assay (FoundationOne), the presence of which correlated with the results from multiprobe fluorescent in situ hybridization (FISH) testing.

The relevance of altered HSF2 expression was elucidated by comparing the genomic profile with that of known tumor suppressors or oncogenes in 85 PrCa samples displaying complete mRNA, copy-number and sequencing data.24, 25, 26 HSF2 was deregulated in 20% of the PrCa tumors, of which the majority (88%) showed a reduction in HSF2 expression level (Figure 1b and Supplementary Figure S1a).

Penn State's Schuster says that "together with genomics, the most important research will be in bioinformatics, where you can correlate temporal or genomic profiles with chemical, mass spectrometry, and genetic data.

We first compared the V+ genomic profile with bees that show heightened arousal due to exposure to alarm pheromone (unpublished data).

Since acquired changes in gene expression may be influenced by both genetic and epigenetic factors in humans, the objective of this study was to develop an approach for integration of global cancer-specific epigenomic and genomic profiles with gene expression, and study these changes in two well-characterized OS cell lines.

The IBD isolates, obtained from patients with UC and CD, displayed remarkably heterogeneous genomic profiles with little or no evidence of group-specific determinants.

In this review, we outline the current methods and those in development for isolating single cells and analyzing their genomic profile, with a particular focus on profiling genomic copy number.

They suggested that a tumour genomic profile with no alterations (flat profile) by MLPA can be caused by tumour cell content below 60%, or by NBs samples with a higher amount of Schwann cells (Ambros et al, 2011).