Here, we compare McyB1 and McyC A domains in strains from the three main microcystin-producing genera: Anabaena, Microcystis and Planktothrix to investigate the role of genomic processes in the reshaping of microcystin genes, enzyme complexes and corresponding peptides.
In this context, the percentage of response to CuSO4 in this study was not low; this percentage was similar or higher than that shown in other dinoflagellates, suggesting that the algicide might considerably affect molecular genomic processes in C. polykrikoides.
VDR and VD3 regulate many transcriptional targets, but their regulation of cellular processes is not limited to transcription; VDR and VD3 also have non-genomic processes in the cell.
JMJD2 lysine demethylases (KDMs) participate in diverse genomic processes.
These intrinsic features of the genome may have the potential to dictate the observed DNA methylation changes [ 18], and provide a description of the genomic processes underlying differential DNA methylation in cancer.
It is not surprising that these structural properties can have a large impact, as most genomic processes involve some sort of change in the DNA structure such as the denaturation required prior to the start of duplication and transcription, protein- induced deformation at DNA-protein complex formation, or the extensive nucleosome packaging of an entire genome.
Considering the differences that the adopted LD method could have with other methods to identify SS, LD methods may detect regions that haplotype based-methods such as EHH [ 67], iHs [ 67], Voight's iHs [ 68], and Rsb [ 65] might not detect, because genomic processes such as insertion/deletion (in/del) and other CNV produce LD patterns that may not be accounted for in the haplotype construction.
By identifying these residual footprints of genomic evolutionary processes in the form of "signatures of selection," we hope to gain valuable insight into the evolutionary past of a species.
Alternatively, 1,25D may mediate growth regulation in MCF7 cells via non-genomic processes [ 5, 6, 27].
By binding to cysteine residues or generating reactive oxygen species Risso-de Faverneyy et al. 2001), Cd has been shown to influence genomic and postgenomic processes in liver, kidney, lung, and brain (Minami et al. 2001).
The finding that the majority of misregulated genes in embryos with a neurodegenerative phenotype was upregulated adheres to a general trend established by genomic studies of neurodegenerative processes in Drosophila CNS tissue, for example, in parkin mutants [ 34] and in flies with neurodegeneration caused by transgenic expression of alpha-synuclein or mutated tau[ 25].
