Sentence examples for genomic predisposition from inspiring English sources

This is also helpful when unanticipated concentration increases exist, e.g., drug drug interactions or genomic predisposition.

It is merely a marker for genomic predisposition to breast cancer.

Subsequent evolvement of pathogenicity arising from such genomic predisposition proceeded differently then in the highly virulent examples TBCF10839 and CHA.

To our knowledge, other shared susceptibility loci have not been found, suggesting that type 2 diabetes and sIA disease do not share genomic predisposition.

DNA reflects our genomic predisposition and there will be changes in RNA that we can detect with chips, but what is probably most important is how proteins are expressed.

The resulting data will reveal the spectrum of rare single nucleotide and insertion-deletion variants, and hopefully will shed additional light on the genomic predisposition to the disease of interest.

The global epidemic of obesity represents a combination of rapidly changing, culture-based behavior changes and discordant genomic predispositions that cannot be ignored.

Indeed, the possibility of screening participants for certain genomic predispositions to drug response (e.g., testing for specific major drug metabolism enzyme alleles) could provide companies better chances of obtaining a positive response in the majority of individuals during clinical trials.

ATM is the protein product of the gene mutated in the human genetic disorder ataxia-telangiectasia (A-T), which is characterized by neuronal degeneration, immunodeficiency, sterility, genomic instability, cancer predisposition, and radiation sensitivity.

The discovery that BRCA1 and BRCA2 are involved in HR explains, at least partly, the genomic instability and predisposition to cancer that are seen in BRCA carriers.

Mutations in the DNA helicase BRIP1 have been implicated in the aetiology of Fanconi anaemia, a genetic disorder that is characterised by congenital abnormalities, progressive bone marrow failure, genomic instability and predisposition to cancer [ 5- 7].