Sentence examples for genomic pathways from inspiring English sources

Currently, however, the accuracy of the approaches based on genomic pathways is not sufficient to predict the involvement of particular genes in microgravity-induced changes.

Transient and continuous administrations equally increased eNOS expression, implying that a short contact between hormone and cells is sufficient to trigger genomic pathways.

It is how we develop diagnostics, therapeutics and guide health care for patients — it all starts with understanding the biological mechanisms, the genomic pathways and how genotypes and phenotypes are related.

Conclusions: Our data suggest that the kinetics of contact of estrogen with the cells could represent a sensor for estrogen receptor (ER) signaling towards non-genomic or genomic pathways.

Pathology at Yale has many "firsts" to its credit, including leadership in documenting the pathology of pandemic flu, radiation injury, and environmental lung disease; methods for the diagnosis and assessment of lymphoproliferative disorders and genomic pathways of tumor resistance to targeted therapeutics.

The U.S. national labs are using deep learning to understand our genomic pathways, to advance drug development, and to improve cancer population health.

Ligand-activated ERs drive gene cascades comprising primary genes, whose transcription is directly controlled by the hormone through physical interaction of ERs with regulatory sites in the genome (genomic pathway) and/or with signal transduction effectors (non genomic pathway), as well as downstream genes whose activity depends upon the functions encoded by the primary responders [ 1, 4].

First, a more detailed elucidation of AM-EMF-induced genomic pathway changes is needed in order to put the results on a firmer mechanistic basis.

In hormone-dependent breast cancer, estrogen receptors are the principal signaling molecules that regulate several cell functions either by the genomic pathway acting directly as transcription factors in the nucleus or by the non-genomic pathway interacting with other receptors and their adjacent pathways like EGFR/IGFR.

This study is the first to conduct an integrative genomic pathway-based analysis with a graph-based learning algorithm.

We also thank our collaborator John Ioannidis for useful discussion and advice regarding our genomic pathway approach.