It operates on the amino acid sequence level to be insensitive to codon usage adaptations and clusters groups of exons disregarding order to handle diversity in genomic ordering between genomes.
Both genomes share several syntenic gene blocks in the same genomic order, although two gene blocks are in inverted orientation and three tRNA genes are translocated.
Like those of their human homologs, the genomic order and arrangement of the four mucins within the cluster of mucin genes are conserved.
The data in Figure 5 indicate that the genomic order was conserved in the pathogenic strains, and those closely related to them.
Samples are represented by rows, genomic regions by the columns sorted on genomic order.
In brief, we have shuffled the natural order of genomic bins in order to minimise the influence of the genomic order of bins with identical values.
In other cases, the first gene encountered in genomic order among multiple equidistant genes not overlapping the given DM site was chosen as the tiebreaker.
To identify the alterations of copy number along the genome, we compared the distribution of the ratios in a sliding window of 20 clones in genomic order with a "null distribution" using a t-test.
We constructed Oxford grids (Edwards 1991) that lined up all 974 gar markers in their genomic order along the horizontal axis and plotted the position of each human ortholog on the human genome displayed along the vertical axis.
