Sentence examples for genomic modulation from inspiring English sources

Septic shock generates a massive genomic modulation with more than 71% of the host transcriptome altered during the first 48 h after shock.

1,25(OH)2D3 achieves this change to the 'signaling landscape' by (i) direct genomic modulation of the level of expression of key regulators of cell signaling and differentiation pathways, and (ii) activation of intracellular signaling pathways.

The genomic modulation occurring in these MSC spheroids is thus of essential importance for understanding their uniqueness and therapeutic potentials.

The present study sheds light on the genomic modulation of the immune response against APEC infection in chickens.

The present study provides evidence, for the first time, that aspirin treatment affects the platelet protein pattern through MK genomic modulation.

These results suggest that there is differential genomic modulation in response to single-strand or double-strand DNA damage in S. cerevisiae.

But, the niche specific genomic modulations may not override the lineage-specific divergences of the microbiome components.

This non-genomic modulation of estrogenic effects of PAHs by PKC activation may have to be considered when considering the deleterious effects of these environmental contaminants towards the endocrine system.

The lack of correlation between AnxA1 gene product and protein is intriguing though it should be said that glucocorticoid- regulation of the AnxA1 pathway is multifaceted; thus, non-genomic modulation 48 with release of the protein, for instance, could account for apparent lower tissue levels of the AnxA1 protein.

Statistics of the gene signatures are further summarized in Table S2 (Additional File 1) with respect to ten functional categories: (1) tumor versus non-tumorous liver comparison, (2) survival/recurrence, (3) cirrhosis/dysplasia, (4) etiology, (5) differentiation, (6) invasion/metastasis, (7) genomic alterations, (8) modulation by a gene/protein factor, (9) HCC subgroups, and (10) other nature.

In addition, long non-coding RNAs are considered to be involved in the regulation of gene transcription, both by controlling the basal transcriptional machinery and by gene-specific regulation via recruitment of epigenetic modifying factors to genomic loci, and modulation of mRNA splicing, as well as translation (Huang et al., 2012b).