Sentence examples for genomic modifications that from inspiring English sources

In order to get some insights into genomic modifications that can occur in vivo, we sequenced these three isolates.

The in vivo passage, despite the small numbers of divisions, permits the selection of numerous genomic modifications that may account for the high capacity of the strain to disseminate.

Epigenetic regulation refers to heritable factors of genomic modifications that do not involve changes in DNA sequence.

Copy number variation is a class of structural genomic modifications that includes the gain and loss of a specific genomic region, which may include an entire gene.

There is an ancient [ 1] but still active debate in the molecular biologist community about the relative contribution of structural genomic modifications [ 2] that could account for the phenotypic differences observed between primate species, particularly in the emergence of new brain structure and functions [ 3, 4].

Thus, the occurrence of NFI at genomic boundaries correlates with specific histone modifications that contribute to gene expression regulation but not with structural boundaries involving the nuclear lamina.

As genomic repeats are known to be enriched for H3K9me3 and H4K20me3, chromatin modifications that are associated with heterochromatin, all ATRX-binding sites across the genome also were tested for association with these two repressive modifications.

Genomic imprinting is an epigenetic process that involves DNA methylation and histone modifications that distinguish the expression of maternal and paternal alleles [ 1].

Successful cloning by SCNT depends on erasure of somatic cell epigenetic modifications (e.g. histone acetylation and genomic DNA methylation) during pre-zygotic reprogramming, followed by a post-zygotic establishment of embryonic modifications that regulate transcription [ 43, 44].

Comparing the genomic sequence and RNA-Seq data obtained from C. graminicola strain M2 offered the opportunity to identify nucleotide modifications that occurred due to RNA editing.

Our data showed that, despite the small number of in vivo generations between the contaminating and the bloodstream isolates, limited genomic modifications have been selected that may account for the ability of the strain to increase its invasiveness.