Sentence examples for genomic methods we from inspiring English sources
To quantify differences in tumor cell signaling that are transparent to genomic methods, we established a super-SILAC internal standard derived from NSCLC cell lines grown in vitro and labeled with heavy lysine and arginine, and deployed them in a phosphoproteomic workflow.
Through cytogenetic and comparative genomic methods, we established that OTOP1 is the boundary gene of an inversion polymorphism on human chromosome 4p16 that originated in the common human-chimpanzee lineage more than 6 million years ago.
Among the 30 middle meiosis genes that were not identified before by genomic methods, we found genes encoding important meiotic cell cycle regulators such as Clb1 ([ 29]) and Hos4 (part of the Set3 complex [ 30]), and other cell cycle regulators such as Apc9 and Cdc37.
Using multiple high-resolution genomic screening methods, we identified a single locus, adherens junctional associated protein 1 (AJAP1) on chromosome 1p36 that is lost or epigenetically silenced in many glioblastomas.
Based on two different genomic search methods we have found between 1200 and 1300 LTR REs of four distinct families within the Silurana genome, containing at least LTRs and a retrotranscriptase ORF.
In this study, we used comparative genomic methods to infer possible functional elements in the coding regions of mammalian Hox genes.
Using genomic sequences (see Methods) we predicted 111 cases of alternative splicing, including conserved ones such as Clathrin light chain (contig7735 and contig8467, See Additional file 5).
Anne O'Donnell Luria, M.D., Ph.D. The Broad CMG applies large-scale genomic methods - exome, whole-genome and transcriptome sequencing - to thousands of undiagnosed rare disease families to drive novel disease gene discovery.
In this report, we applied cytogenetic and genomic methods to investigate the organization of rRNA genes among cichlid fishes.
Here we provide a brief review of how genomic methods can be applied to study the genetics and evolution of animal behavior.
This fundamental problem was recently solved with the development of single-cell genomic methods that allow the generation of draft genome data from cells collected in the natural environment25,26,27,28.
