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The main features of MicrobeDB are automated downloading of archaeal and bacterial genomes from NCBI, organized storage of the flat files, annotations and genomic metadata stored in a MySQL database, and a Perl API database for interacting with the data.
GT includes support for SSL encrypted data channels, preauthentication and authorization keys and genomic metadata integration.
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The ontology comprises ∼1600 terms and is part of recommended (meta- genomic meta- genomicdards (Yilmetadatal., 2011).
The mission statement of the GSC is to work toward the implementation of new genomic standards for metadata and methods of capturing and exchanging that metadata.
For example, MIGS (Minimum Information about a Genome Sequence) and related MIxS standards require specific metadata for genomic sequences (Field et al., 2008; Yilmaz et al., 2011).
One such revolutionary resource which integrates different forms of federated information comprising of genomic sequences and associated metadata relating to various marine microbial sequencing projects is CAMERA (Community Cyberinfrastructure for Advanced Marine Microbial Ecology Research and Analysis) [29].
We chose the Chado database to store the modENCODE experimental metadata and genomic features because of familiarity, availability of tools, nominal compatibility with FB and WB and browser neutrality.
The vetting tool builds a full model of the experiment, including all metadata and genomic features, before writing ChadoXML to enable crosschecking of dependent references across fields and features.
A third and related ethical challenge in data sharing identified by respondents concerned the implications of the absence of any accompanying contextual knowledge, what we would like to call 'ethical metadata' , when genomic data are released.
It requires powerful statistical and machine learning methods and can be facilitated by the possibility of producing visualizations of intermediate results, by the automation of complex workflows such as cross-validation or parameter searches, and by easy access to biological metadata and genomic databases.
Created from 17.4 million genomic sequences and their associated metadata, ATLAS in silico is coming to Hobart's Mofo this week.
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CEO of Professional Science Editing for Scientists @ prosciediting.com