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The diagonal elements of the GRM and the proportion of the genome where SNPs are homozygous are both examples of genomic measures that can be used to estimate the level of inbreeding across the genome.
Similarly, for the genomic measures, samples were binned into one of four groups based on data quartiles for each measure.
Genomic measures can be used instead of pedigree-based inbreeding to estimate inbreeding depression.
There have been relatively few studies on inbreeding depression using genomic measures of inbreeding.
Genomic measures of inbreeding were all higher for the Jersey than for the Holstein population (Table 2).
Again, this is likely to be due to a lack of knowledge, sufficiently comprehensive genomic measures and appropriate training datasets.
Similar(41)
Gene order conservation is a useful genomic measure for predicting functional interaction and relatedness among genes within a cluster.
The omnipresence of the glycolytic enzymes makes for a crude but standardized genomic measuring stick, comprising an ideal platform for studying pseudogenes.
The correlation between ROH and pedigree-based inbreeding was strongest for ROH that consisted of 10 SNPs (0.58 Mb) and stronger than the correlation of any other genomic measure with pedigree-based inbreeding (Table 3).
As glycolysis is such a highly conserved and fundamental metabolic pathway, the pseudogenes of glycolytic enzymes comprise a standardized genomic measuring stick and an ideal platform for studying molecular evolution.
We also assessed genomic instability measures and found a correlation of the number of higher amplitude gains with poorer overall survival.
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