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Here, we introduce methods that integrate the strength of association between genotype and phenotype, the variability in the genetic backgrounds across populations, and the genomic map of tissue-specific functional elements to increase trans-ethnic fine-mapping accuracy.
Genomic map of the target locus was constructed on the basis of both reference sequences.
The genomic map of Actinoplanes sp. N902-109 has been elucidated in our laboratory.
Genomic map of target gene were established through three rounds of linkage analysis using genomic position-ready molecular markers (He et al. 2012).
However, a genomic map of the human X centromere has provided new opportunities to explore genomic architecture of a complex locus.
(A ) Genomic map of the mouse Otx2 locus.
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In combination with genomic mapping of the ST40 draft genomes against the D32 template, results revealed a comparably high level of diversity in plasmid content [ 81] and strain-specific phage patterns.
Availability of a reference genome sequence both speeds this resequencing operation and allows genomic mapping of polymorphisms.
Genomic mapping of transcripts to the M. truncatula 3.5 genome were performed using GMAP [ 44], and post-filtered for identity and coverage requirements.
Conservation of transcription at cis-NAT loci in Arabidopsis lyrata was determined by genomic mapping of full-length transcripts against the A. lyrata genome, using BLAT [ 19].
This result was confirmed by a preliminary survey of genomic maps of positioned nucleosomes of the D. melanogaster and P. falciparum genomes and of the human chromosome 20.
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