'genomic manipulation' is correct and usable in written English.
You can use it when referring to the manipulation of the genome, usually in a scientific context. For example, "This research on plant species involves genomic manipulation in order to create a higher yield of crops."
Mice are one of the most common and convenient mammalian models for studying the pathogenesis and immunology of many influenza viruses because of their well-characterized genome, advanced techniques for genomic manipulation, the convenient availability of mouse-specific immunological reagents, easy husbandry and low cost.
We have also started to identify readers of chromatin modifications in the context of nucleosomes and chromatin, and genomic manipulation techniques enable the large-scale characterization of protein protein interactions by genome-wide endogenous tagging of proteins.
"This is just an attempt to monopolise, through the patenting system, essentially all the tools for genomic manipulation," Sulston said.
Nevertheless, several Gram-negative bacteria have been also used in BDS because they are endowed with some properties, e.g., broad metabolic versatility and easy genetic and genomic manipulation, that make them suitable chassis for systems metabolic engineering strategies.
Given these difficulties, their use for large-scale genomic manipulation or genetic screens has been limited.
Genomic manipulation of hepatic FGFR4 has uncovered roles of endocrine FGF signaling in both metabolic and cellular homeostasis.
Results presented here suggest caution towards approaches involving genomic manipulations when developing rationally designed ASFV vaccine strains.
Future applications may potentially include genomic manipulations, for example, site-specific integrations, deletions or substitutions within precise regions of the genomes of mammalians and other organisms.
Mutational and transcriptional patterns indicated a series of genomic manipulations that not only proved the causative effect of mutB2 (coding for methylmalonyl-CoA mutase large subunit) and argS2 (coding for arginyl tRNA synthetase) mutations on the overproduction of rifamycin, but also constituted a rational strategy to genetically engineer a reference strain into an overproducer.
In addition, it will provide the opportunity to develop recombinase-mediated techniques for genomic manipulations.
Importantly, these novel approaches enable homologous recombination as a means for precise genomic manipulations in medaka.
