To better understand the genetic variation and antibiotic resistance mechanisms of this bacterium at the genomic level, we reported high-quality draft genome sequences of 8 clinical isolates with various sequence types and drug susceptibility profiles.
To investigate the links between H2BK123ub1 and these H3 methylations at the genomic level, we compared the map of H2BK123ub1 occupancy to published genome-wide maps of H3K4me3, K36me3 and K79me2/me3 methylation (Additional file 1, Figure S2, S3).
At the genomic level, we observed extensive rearrangements in specific targeted loci linked to transgene integration sites.
That is, when looking for race at the genetic or genomic level, we can come away with research findings that are consistent with any "racial" classification scheme one wishes to find.
In order to understand the differentiation at the genomic level, we have determined the complete sequence of an A.II strain (WY96-3418) and compared it to the genome of Schu S4 from the A.I population.
To detect any possible correlation between lupus and other diseases at the genomic level, we compared the differentially expressed genes between SLE and control samples and other disease gene sets.
To experimentally validate the CNVs at a genomic level, we randomly selected 6 CNV regions (at 4p12, 4q13.2, 6q14.1, 6q27, 12p13.31, and 15q14; Table 1) and examined their copy number by real-time quantitative PCR QPCRR) in fibroblasts or LCLs from 51 Amish family members.
At the genomic level, we identified variety-specific SNPs.
As a final test of Nrf2 recruitment to the HAMP promoter at the genomic level, we performed ChIP assays.
Given the extensive differences observed at the genomic level we were interested to check different MCF-7 sublines at the transcriptome level.
