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Intravital imaging has been combined with technologies for genomic level analysis of the metastatic pathway only to a limited degree.
To understand the mechanisms of desiccation survival we have initiated a genomic level analysis of gene expression during anhydrobiosis of P. murrayi.
Such approaches could now be further developed to link cellular behavior in vivo with a molecular level analysis, because single-cell genomic level analysis has become feasible (Navin et al., 2011).
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Methods to map sequence based markers and to compare maps with relevant model systems are crucial to extend genomic-level analysis to non-model species [ 54].
On a genomic level, comparative analysis between cotton, Arabidopsis, and Vitis genomes illustrates the potential for translational genomics across these species, and several regions with an unusually high degree of conserved collinearity may be interesting for further research.
Besides the research on genomic level, transcriptome analysis is also necessary to compare the differential gene expression between the two sexes to fully understand the genetic basis of sexual dimorphism.
For the genomic level of 5mC analysis, bisulfite treatment can be followed by next generation sequencing (BS-seq) method.
To overcome this problem, also considering that random, non-sequence specific T-DNA integration has been shown to be the main outcome of ATM-transformation in other fungi (Bundock et al. [2002]), we mapped T- DNA insertions at the genomic level by hybridization analysis conducted with two specific probes (named P1 and P2). Figure 2 Following the fate of the T-DNA in pABr1-transformed hyphae.
Stress-related differences were visible at the genomic level through PCA analysis highlighting the high sensitivity of BALB/cJ animals to environmental stressors.
However, the availability of genome sequences allows us to mine for SSRs at the genomic level in silico, and analysis of these SSRs has provided insight into their distributions, putative functions, and evolution [ 14, 15].
3-79) (Wang et al. 2012; Li et al. 2014; Zhang et al. 2015; Yuan et al. 2015), we tried to mine the important genes related to fiber development and biotic and abiotic stresses in the whole genomic level for their functional analysis.
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