Sentence examples for genomic functions including from inspiring English sources

The loss of function in the DNA repair category may have promoted the accumulation and spread of pseudogenes in NoAz genomic functions, including in the DNA replication process.

It modulates genomic functions including the regulation of gene differential expression, cellular differentiation, embryonic development, and genomic imprinting [ 28].

Bifidobacteria are notoriously recalcitrant to genetic modification, which prevents exploration of their genomic functions, including those that convey (human) health benefits.

Indeed, lncRNAs have been identified using a variety of methods, and the number of specific lncRNAs shown to influence genomic functions, including roles in imprinting [ 45], enhancer functions [ 46, 47], X chromosome inactivation [ 48], chromatin structure [ 49] and genomic rearrangements during the generation of antibody diversity [ 50], is increasing.

P53 is a key regulator of stem cell homeostasis that impacts an array of cellular functions including genomic surveillance, cell-cycle regulation and apoptotic and inflammatory response.

BRCA1 plays a vital role in the maintenance of genomic integrity through multiple functions including DNA damage repair, transcriptional regulation, a cell cycle checkpoint and protein ubiquitination.

Our analysis revealed that genomic variations, in particular mobile functions including phages, prophages, transposable elements, and plasmids underlie the metadata structuring in each of the three niche dimensions.

Transposable elements transform themselves over evolutionary time from mediators of havoc (which they invoke as they jump into and destroy useful genomic loci) to bearers of novel functions, including regulatory elements for neighboring genes.

In mammals, DNA methylation has several well-characterized regulatory functions, including X chromosome inactivation, genomic imprinting, alternative splicing, and cellular differentiation (Schwartz and Ast 2010).

The multi-integrase HAC vector has several functions, including gene integration in a precise locus and avoiding genomic position effects; therefore, it was used as a platform to investigate integrase activities.

Such cell cycle disruption is associated with genomic instability, due to mutations and chromosomal aberrations that disrupt critical housekeeping functions, including DNA repair and cell cycle checkpoints.