Sentence examples for genomic functions and from inspiring English sources
In addition, the ChIP-chip and ChIP-seq technologies enable researchers to investigate the distribution of the histone marks (and other proteins) on the genome at a high resolution, which led to the discovery that the binding patterns of the proteins and histone marks over the genome are also highly informative in predicting genomic functions and annotations [ 13, 15- 17].
Our present studies provide a useful tool for future research on genomic functions and molecular pathogenesis of DHAV-3.
Genome-wide studies of histone modification patterns have shown that specific histone modifications are associated with specific genomic functions and that these patterns are altered in cancer.
Therefore, other important information across prokaryotic genomes, such as genomic function and genomic structure, should also be considered for orthologous genes identification.
For example, they suggest that we should rethink the relationship between genomic function and evolutionary conservation.
First, orthologous genes are determined by sequence similarity, genomic function, and genomic structure information.
Sequence similarity is calculated by BLAST, whereas genomic function and genomic structure are estimated by COG and operon annotation, respectively.
In the first step, we compute orthologous genes by considering sequence similarity, genomic function, and genomic structure information.
We can see that many special genes are reduced by considering genomic function and genomic structure information.
From our perspective, identifying over represented GO terms can provide insight into regional genomic function, and while statistical methods of measuring GO term distribution vary, we have adopted a commonly used method based on the hypergeometric distribution [ 12].
The results provide clear support for application of this approach to other tissues, which when coupled with this research will clarify with high resolution pan-Nematoda genomic functions as related gene and protein expression in adult nematodes.
