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Computational prediction of the phenotypic propensities of noncoding single nucleotide variants typically combines annotation of genomic, functional and evolutionary attributes into a single score.
On the computational side, Dr. Campbell has developed novel multi-scale models of the heart that integrate genomic, functional, and anatomical data to predict behavior of the intact organ.
Genomic, functional, and structural mitochondrial alterations have been associated with cancer.
We showed that gene constellation groupings are correlated to a number of genomic, functional and evolutionary properties (Tables 1- 2).
We have examined a non-exhaustive set of genomic, functional, and evolutionary properties for correlation with gene constellations as defined by our classification scheme.
These sequences will greatly facilitate the identification of candidate genes, allowing integration of both genetic and genomic (functional and structural) data.
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Primates are an excellent model to study given the abundance of genomic, functional genomic, and phenotypic data available.
However, in recent years other technologies have been used to overcome some of these issues through genomic, functional genomic and biotechnological approaches.
We have shown that chromatin architecture is sufficient to identify and characterize genomic functional elements.
New informatic approaches are emerging which are capable of integrating genomic and functional datasets and also making use of data available through published resources.
Version 5.1 of PlasmoDB, a resource for malaria parasite genomic and functional genomics datasets, was released in August 2006.
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