Sentence examples for genomic function is from inspiring English sources
A well-characterized example of minisatellite genomic function is that associated with the human HRAS1 oncogene (Capon et al. 1983).
The surest indicator of the existence of a genomic function is that losing it has some phenotypic consequence for the organism.
Recent work has highlighted how chromosomal interactions, nuclear position and genomic function are inter-linked.
The inconsistency in genomic locations suggests that their potential function is not confined by the local genomic context, which means not being confined by the genes harboring it, though there are other constraints to limit their location, e.g., relative distance conservation [4].
Either way, when p53 function is jeopardized, genomic instability and uncontrolled cell proliferation are facilitated.
However, in contrast to their abundance and importance in neurobiology, large-scale genomic information relating to neuronal function is limited to one species, A. californica [ 38].
These findings show that Scc4 targets cohesin loading to a specific genomic locus and that this function is separable from its essential role in establishing sister chromatid cohesion across the genome.> We prepared full-length Scc2/4 by co-expressing both proteins in baculovirus-infected insect cells.
Chromatin is a complex of DNA, RNA, and proteins whose primary function is to package genomic DNA into the tight confines of a cell nucleus.
The inability to directly test and perturb the regulatory activity of large numbers of DNA sequences has hindered efforts to discover how cis-regulatory function is encoded in genomic sequence.
The mechanism of this acceleration in tumor initiation and/or progression is unknown, although loss of Brca1 function is associated with genomic instability [19].
MSH2 and other MMR proteins are highly expressed in normal cells, and their key function is to maintain genomic stability by correcting DNA damage and replication errors from endogenous and exogenous sources.
