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In particular, high-throughout sequencing technology has recently become a powerful tool that allows to profile a genomic expression pattern and to measure modest changes among different samples at unprecedented perspectives [ 16, 17].
We have found that advanced age is one of the greatest predictors of poor clinical outcomes after severe blunt traumatic injury with hemorrhagic shock, and that advanced aging is associated with a unique genomic expression pattern in circulating neutrophils.
However, recent molecular findings confirmed the asymmetric genomic expression pattern in natural and synthetic allopolyploid plant species, but the predominant transcript expression of one genome over the other genome(s) vary from gene to gene [ 51].
Microarray studies may analyse genomic expression pattern changes induced by an siRNA or shRNA, but even for these single-target tools, multiple changes will arise secondary to the silencing of the single intended gene.
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This study maps the genomic expression patterns in the hearts of the db/db murine model of diabetes and illustrates the impact of rosiglitazone on these patterns.
In conclusion, this study has mapped the genomic expression patterns in the hearts of the db/db murine model of diabetes and the effects of rosiglitazone on these patterns.
Clues for mitochondria functions impairment in HIBM were also found previously in genomic expression patterns comparison of muscle specimens from 10 HIBM patients carrying the M712T mutation and presenting mild histological changes, compared with 10 healthy matched control individuals [24].
Our aim was to identify the molecular profiles that contribute to genomic expression patterns after human spontaneous ICH and to compare our results with other human studies with similar approaches.
Remedies modulate specific genomic expression patterns as well [ 9, 163, 164].
These findings demonstrate that tissue repair has distinguishable and different genomic expression patterns in mucosal and cutaneous sites.
The concept of an effective TRN thus allows quantifying the contribution of digital control to genomic expression patterns.
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