Sentence examples for genomic evolutionary rates from inspiring English sources

To estimate genomic evolutionary rates of insect lineages, we formed 439 protein clusters derived from cDNA or EST data from beetle (Tribolium castaneum), fly (Drosophila melanogaster), mosquito (Anopheles gambiae), aphid (Acyrthosiphon pisum), and human (Homo sapiens).

The degree of evolutionary conservation was scored by Genomic Evolutionary Rate Profiling.

Ensembl provides a nucleotide level GERP (Genomic Evolutionary Rate Profiling) scoring [43], that reflects the amount of inferred substitution, which in turn allows the identification of constrained elements.

Genomic evolutionary rate profiling (GERP) estimates position-specific evolutionary rates and identifies candidate-constrained elements [ 24].

Finally, we prioritized the variants according to scores from prediction programs (PolyPhen, Grantham, Phastcon, or Genomic Evolutionary Rate Profiling).

We also examined sequence conservation at Rxrα binding sites using genomic evolutionary rate profiling (GERP) scores [ 30].

Genomic Evolutionary Rate Profiling (GERP) is a method for producing position-specific estimates of evolutionary constraint using maximum likelihood evolutionary rate estimation [ 54].

The bioinformatics pipeline identified mutations expected to have deleterious impact on protein function based on PolyPhen predictions and conservation scores (Genomic Evolutionary Rate Profiling).

Genomic Evolutionary Rate Profiling (GERP) (Cooper et al., 2005 ): this approach assigns a conservation score to each site in an alignment, independently of neighboring sites.

Of note, all three mutations are in highly conserved regions as evidenced by the high genomic evolutionary rate profiling score and thus are likely to be biologically significant.

Genomic Evolutionary Rate Profiling (GERP) is a method to assess regions that have been subject to purifying selection and are enriched for functional elements [ 26].