Sentence examples for genomic evolutionary rate from inspiring English sources
The degree of evolutionary conservation was scored by Genomic Evolutionary Rate Profiling.
Ensembl provides a nucleotide level GERP (Genomic Evolutionary Rate Profiling) scoring [43], that reflects the amount of inferred substitution, which in turn allows the identification of constrained elements.
Genomic evolutionary rate profiling (GERP) estimates position-specific evolutionary rates and identifies candidate-constrained elements [ 24].
Finally, we prioritized the variants according to scores from prediction programs (PolyPhen, Grantham, Phastcon, or Genomic Evolutionary Rate Profiling).
We also examined sequence conservation at Rxrα binding sites using genomic evolutionary rate profiling (GERP) scores [ 30].
The bioinformatics pipeline identified mutations expected to have deleterious impact on protein function based on PolyPhen predictions and conservation scores (Genomic Evolutionary Rate Profiling).
To estimate genomic evolutionary rates of insect lineages, we formed 439 protein clusters derived from cDNA or EST data from beetle (Tribolium castaneum), fly (Drosophila melanogaster), mosquito (Anopheles gambiae), aphid (Acyrthosiphon pisum), and human (Homo sapiens).
Surprisingly, these regions of low methylation in blood show no difference regarding genomic location, genomic content, evolutionary rates, or histone marks when compared to other tDMPs.
Then, comparisons of genomic structure, molecular evolutionary rate, and expression pattern of the two Ddx3 genes in Japanese flounder were performed; results revealed probable subfunctionalization of teleost duplicated Ddx3 genes.
A high controversy in evolutionary genomics is around the pervasive yet weak genomic correlations with the evolutionary rate of protein sequence [ 1, 2].
Using a collection of expressed sequence tag (EST) data, we re-evaluated the correlation of tissue specificity with genomic structure, phyletic age, evolutionary rate and promoter architecture of human genes.
