Exact(2)
Even though most recurring meta- and synchronous tumors showed a clonal relationship, no simple genomic evolution from chronologically early to late tumors could be invoked.
Therefore, the sequence evolution toward GC- and AT-richness in the peritelomeric and pericentromeric region of neo-sex chromosomes, respectively, must be a consequence of genomic evolution from autosomes to sex chromosomes specifically in T. muenninki lineage.
Similar(58)
The manuscript correctly makes clear that (i) genomic evolution is far from 100% tree-like, (ii) drawing a tree does not mean assuming that genomic evolution is 100% tree-like, and reviews the way these two basic-looking statements have been acknowledged, and their relative importance weighted, by the scientific community.
A comprehensive view of recombination's effects on genomic evolution requires whole-genome sequences from multiple isolates, something that has only recently been possible on sufficiently large scales (e.g., He et al. 2010, Joseph et al. 2012, Namouchi et al. 2012).
These data suggest that, independent from patterns of genomic evolution, the mutational processes that shape the MM cell genome are already operative at the smoldering stage.
The present evaluation of the genomic evolution pattern suggests that chloroviruses differ from that described in the related Poxviridae and Mimiviridae.
Importantly, recombination events between insect viruses from unrelated families and genera might drive baculovirus genomic evolution.
Genomic evolution of T-cell lymphoma in our mouse model was different from that in humans.
Moreover, the genetic variation induced by asymmetric somatic hybridization has different characteristics from those induced by allopolyplodization, demonstrating the specific genomic evolution in somatic hybrids.
The increasing availability of mitochondrial (mt) sequence data from various yeasts provides a tool to study genomic evolution within and between different species.
From these data, we construct a putative overview of the genomic evolution of human prostate cancer.
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