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Such cases represent recurrent genomic evolution due to selective environmental pressures acting at on a specific subset of lineages.
Despite advances in the understanding of genomic evolution due to hybridization events among species that have long diverged (Clarke et al. 2002; Rieseberg et al. 2003), only scant information is available on the evolution of genomes of fungal pathogens undergoing hybridization (Brasier and Kirk 2010).
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In addition, it might be due to genomic evolution of serial clinical strains in patient under therapy.
This indicates that the higher number of Hsp90 members in poplar is due to the expansion of gene families during the genome duplication and the genomic evolution followed.
The foremost feature of duplicated genomic regions is that they undergo concerted evolution due to the exchange of genetic information via interlocus gene conversion (IGC) (Nagylaki and Petes 1982; Ohta 1982).
The similar genomic organization in Drosophila and vertebrates is widely considered as a result of convergent evolution, due to independent tandem gene duplications.
Subclonal architecture and genomic evolution of small-cell lung cancer (SCLC) under treatment has not been well studied primarily due to lack of tumor specimens, particularly longitudinal samples acquired during treatment.
The genomic evolution of tRNA gene thus may be linked to the evolution of genome organization.
Due to the difficulties inherent in sampling tumor at progression, serial analysis of plasma DNA before and after treatment provides an opportunity to study the genomic evolution of SCLC during and after treatment.
These data suggest that ctDNA sequencing is promising to delineate genomic landscape, subclonal architecture, and genomic evolution of SCLC.
Bolli, N. et al. Heterogeneity of genomic evolution and mutational profiles in multiple myeloma.
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